Despite its widespread occurrence, the genetics of fusarium wilt resistance in cotton has still not been clearly elucidated. This is a result, in part, of the complex phenotyping involved, but also, in some cotton growing regions, the compounding effects of root knot nematode interactions with the severity of fusarium wilt symptoms. More importantly, the genetic relationships among fusarium wilt pathogens around the world are complex, suggesting that a single genetic model may not be applicable universally. To elucidate the genetics of fusarium wilt resistance against Australian fusarium wilt pathogens (Fusarium oxysporum f.sp vasinfectum VCGs 00011 & 00012), two genetic families have been used. The purpose of this paper is to present evidence that G. siurtianum and G.barbadense harbour genes of interest for the genetic improvement of cultivated cotton.