There are a number of minor weeds that occur throughout the Australian cotton industry that have considerable potential to spread and become increasing problems. Two of these are anoda weed (Anoda cristata) and velvetleaf (Abutilon theophrasti). Research has been focussed on these weeds in an effort to better understand the biology and lifecycle of these weeds to prevent further spread and to lead to increased management success. This paper briefly outlines that best management of these species can be achieved by controlling successive flushes of seedlings, preventing weed seed set and by rigorous farm hygiene practises. While these practises need to be part of an Integrated Weed Management (IWM) package, the limited suite of herbicides that are currently registered to control anoda weed, and lack of any herbicide registrations for velvetleaf is likely to hamper future management. This paper calls for further herbicide screening and registration of herbicides for both weeds in the Australian cotton industry. At present, one of the best means of management is the maintenance of rigorous standards of farm hygiene, akin to the Collie Clean Go Clean campaign used to prevent the spread of cotton pathogens