A major research effort over the last 13 years by researchers from DPI&F in collaboration with other agencies has sought to understand what strains of the pathogen are present, monitor the distribution of the pathogen and to identify new stains as they emerge. A major focus has been on the development of disease management strategies including exclusion of the pathogen and farm hygiene practices, development of varieties with higher tolerance to Fov, crop rotation options, biological control and silicon fertilisation. The aim of this paper is to summarise some of the research findings of the DPI&F on management of Fusarium wilt of cotton.