In Australian agro-ecosystems pest dynamics are changing, synthetic insecticides production are declining and there is evidence of increasing pest resistance or tolerance to transgenic plants. Thus, a total collapse of agricultural industries in Australia is possible if pest control alternatives such as biopesticides, semiochemicals etc are not produced and made available to farmers to manage pests. Subsequently, the development of biopesticides and semiochemicals to support integrated pest management (IPM) in cotton, grains, pulses and horticultural crops is crucial. But the development of biopesticides and semiochemicals per se will be ineffective unless these products are registered and available in Australia. Hence, the need to develop a commercialization platform to facilitate generation of toxicological and environmental data and to assist commercial partners in registation of these products . The proposed Centre for Biopesticides and Semiochemicals (CBS) aims to fulfil both of these roles.The Centre will function as an integrated network of highly recognized scientists from research provider organizations and universities. The research provider organizations are (1) NSW Dept of Primary Industries; University of Western Sydney (UWS); Centre for Phytochemistry & Pharmacology - Southern Cross University (CPP-SCU); University of New England (UNE); and Cotton Research & Development Corporation (CRDC).Overall the CBS will research and develop biopesticide and semiochemical products for pest management, and, in collaboration with industry partners, make these available to farmers . The development of biopesticide and semiochemical products will support the further development of IPM in cotton, grains, pulses and horticultural crops. The development of biopesticides and semiochemicals per se will be ineffective unless these products are registered and available in Australia. Hence, the CBS will develop a commercialization platform to facilitate generation of toxicological and environmental data and to assist commercial partners in registration of these products in the cotton and other agricultural industries. These biological products will provide economic, environmental and social benefits to agricultural industries.